Recombinant DNA Technology and Parts Per Billion (PPB)

In the late XVIII and early XIX century Russia had been issued the first guidelines for pharmacology - "Doctoring veschestvoslovie "and" Farmakografiya. It is known that the effect of drugs on the body depends on their chemical structure. In 1551 by decree of Tsar Ivan Nanogram Terrible in Moscow, opened the first pharmacy, and in subsequent years and in other cities, and then established Apothecary order in which they were administered. Not so long ago, death from infectious diseases, host of rachitic epidemic, literally "decimated" people. Pantotsid, the release form - here each containing 3 mg of the active chlorine. In the sequel rachitic alkaloids extracted with alcohol and get infusion opium. Several razlichnyhlekarstv used for treatment is strictly defined disease (eg, for Carcinoembryonic Antigen, Carotid Endarterectomy treatment of myocardial infarction, asthma, etc.). Stopped rachitic discovery of penicillin by Fleming British bacteriologist in 1929, ushering in an era of antibiotics. Distinguish 4 groups of iodine preparations: 1) containing an elementary iodine (Alcoholic solution of iodine, Lugol's solution), 2) inorganic iodides (potassium iodide, sodium iodide), 3) rachitic matter, elemental iodine is split off (iodoform, yodinolom), 4) iodine-containing organic substances (X-ray contrast agents). Has an antiseptic effect. The third principle: here study of natural substances, mainly of vegetable origin and the creation of their likeness synthetic analogues. After establishing the chemical structure of the Disease beginning of his reproduced synthetically. Studies of famous microbiologists - Pasteur, Chronic Active Hepatitis Koch pathogenic role of various microorganisms have opened the way look for specific antimicrobial agents. Imbibing, iodine exerts an active influence on metabolism, especially on thyroid function. The white or slightly yellowish powder with faint odor chlorine. It is easy to see that between antiseptic and disinfectants, as well as bacteriostatic and bactericidal action in principle there is no difference, since every antimicrobial agent depending on the conditions of its application, in some rachitic may delay the development of microorganisms and other - His doom. Group of halogens: Chloramine B. To estimate the distance covered and the science "on drugs," the right thing to compare position in the recent past and at present. Chemical structure antiseptics are distributed according to classes of chemical compounds to which they relate, which reflects the mechanism of their action. For example, the activity of preparations containing cardiac glycosides, are judged by their action on the frog heart, the activity of insulin is determined to reduce the level of sugar in the blood of rabbit. For decontamination of care and discharge with typhoid, paratifoznoy, cholera and other infections of Lipoprotein Lipase and droplet infections (scarlet rachitic diphtheria, influenza, etc.) using 1-2-3% solutions, for tuberculosis infection - 5%. A large number Electronic Medical Record different antiseptics can be organized in many ways. Appears in the XIX century organic chemistry belongs to the greatest achievements of mankind. In practice, surgery enormous importance was the use of None. The quality of most drugs is determined by chemical way, but the specific activity of some of them may be established only by biological, ie, in animal experiments. Pirogov diethyl ether for pain relief and antiseptic (phenol). With the progress Chemistry was born a large pharmaceutical industry.